The Centers for Disease Control and Prevention (CDC) is part of the U.S. Department of Health and Human Services and is the primary Federal agency for conducting and supporting public health activities in the United States. Its mission is to create the expertise, information, and tools that people and communities need to protect their health – through health promotion, prevention of disease, injury and disability, and preparedness for new health threats. AU-IBAR through a Memorandum of Understanding with CDC – South Africa conducted continent wide training of (joint) multi-disciplinary rapid response teams in 46 countries. This partnership is expected to fledge even further as AU-IBAR enters into active engagement with zoonotic diseases in the coming months.